Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults

NEJM 2021 January 6 

Http://doi.org/10.1056/NEJMoa2033700

Romana Libster, M.D. Argentina, Fundación INFANT

A year later and evidence based medicine, that is medicine by bureaucratic edict, only now publishes results that, I wager, every clinical physician knew or at least strongly suspected from the outbreak. The president’s physicians at Walter Reed treated appropriately and early. Why were physicians attempting early treatment punished, some even loosing their license or their jobs? If evidence based authorities assessed outcome by correct diagnosis and the experience of the clinical physician and the clinic, they might find a more efficacious treatment for their guidelines, but even then, the protocol would be outdated because medicine moves so fast. 

In the case of this pandemic, lives could have been saved. Convalescent plasma, Ivermectin, Hydroxychloroquine, Vitamin D, C and Melatonin all found advocates. It would not be a secret to also credit the presence of a trusted family physician giving emotional support, mitigating fear, thus strengthening the patient’s immune system spontaneously from within by some ill defined neural-humeral pathway. Yes, early convalescent plasma works, but we knew that all along.