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Type Two Diabetes (T2D)


Cell 150, 1223-1234, 2012
Domenico Accili at Columbia studying mouse Foxo1 gene discovered that pancreatic Islet β cells do not die in type-two diabetes (T2D) but revert back to endocrine progenitor cells that are unable to make insulin. This opens the possibility of treating T2D by turning these dormant cells back to normal. Once more an exciting contribution from genomics.
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